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A Phase 1/2 Trial of ADI-270 (Engineered γ?? Chimeric Receptor [CAR] V??1 T Cells Targeting CD70) in Adults With Relapsed or Refractory (R/R) Clear Cell Renal Cell Carcinoma (ccRCC)

Trial Profile

A Phase 1/2 Trial of ADI-270 (Engineered γ?? Chimeric Receptor [CAR] V??1 T Cells Targeting CD70) in Adults With Relapsed or Refractory (R/R) Clear Cell Renal Cell Carcinoma (ccRCC)

Status: Recruiting
Phase of Trial: Phase I/II

Latest Information Update: 09 Jul 2025

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At a glance

  • Drugs ADI 270 (Primary) ; Cyclophosphamide; Fludarabine
  • Indications Renal cell carcinoma
  • Focus Adverse reactions
  • Sponsors Adicet Bio

Most Recent Events

  • 06 May 2025 According to Adicet media release, the company expect to report preliminary Phase 1 data in the second half of 2025.
  • 30 Apr 2025 Trial in progress poster presented at the 116th Annual Meeting of the American Association for Cancer Research.
  • 03 Mar 2025 According to Adicet Bio media release, data from this study will be presented in a poster presentation by Gregory Vosganian, M.D. on Thursday, March 13, 2025, from 5:00 p.m. - 6:30 p.m. PT, at the upcoming Society for Immunotherapy of Cancer (SITC) 2025 Spring Scientific Meeting taking place March 12-14, 2025, in San Diego, C.A.

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