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A phase I randomized, investigator and participant blind, adaptive, multiple-ascending dose, parallel and four-way crossover, placebo-controlled study to investigate the safety, tolerability, pharmacokinetics, pharmacodynamics, and drug interactions (with midazolam) of RO7308480 following oral administration in healthy participants

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A phase I randomized, investigator and participant blind, adaptive, multiple-ascending dose, parallel and four-way crossover, placebo-controlled study to investigate the safety, tolerability, pharmacokinetics, pharmacodynamics, and drug interactions (with midazolam) of RO7308480 following oral administration in healthy participants

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 22 Nov 2023

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At a glance

  • Drugs RO 7308480 (Primary) ; Lorazepam; Midazolam
  • Indications Anxiety disorders
  • Focus Adverse reactions
  • Sponsors Roche

    • Most Recent Events

    • 16 Nov 2023 Planned initiation date changed to 16 Nov 2023. Added AR as Trial focus as its a phase 1 study.
    • 14 Nov 2023 New trial record
    • 08 Nov 2023 Status changed from recruiting to completed.

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