Phase 1 Trial of the Safety, Pharmacokinetics, Pharmacodynamics, and Preliminary Clinical Activity of RP-3467 Alone and in Combination with Olaparib in Participants with Advanced Solid Tumors (POLAR Trial)
Latest Information Update: 16 Feb 2025
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At a glance
- Drugs Olaparib (Primary) ; RP-3467 (Primary)
- Indications Adenocarcinoma; Advanced breast cancer; Fallopian tube cancer; Male breast cancer; Ovarian cancer; Pancreatic cancer; Peritoneal cancer; Prostate cancer; Solid tumours
- Focus Adverse reactions; First in man
- Acronyms POLAR
- Sponsors Repare Therapeutics
- 09 Jan 2025 According to a Repare Therapeutics media release, Topline safety, tolerability and early efficacy data from this trial expected in Q3 2025.
- 14 Oct 2024 According to a Repare Therapeutics media release, the first patient has been dosed in this study.
- 14 Oct 2024 Status changed from not yet recruiting to recruiting.