Trial Profile

A Phase 1, Multicenter, Open-label Study of REM-422, a MYB mRNA Degrader, in Patients With Recurrent or Metastatic Adenoid Cystic Carcinoma

Status: Recruiting

Phase of Trial: Phase I

Latest Information Update: 27 Oct 2025

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At a glance

24 Oct 2025 According to Remix Therapeutics media release, company announced positive preliminary results from its ongoing Phase 1 clinical trial evaluating REM-422.
24 Oct 2025 Planned number of patients changed from 65 to 100.
13 Oct 2025 According to Remix Therapeutics media release, data from this trial will be presented at AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics, taking place on October 22-26 at the Hynes Convention Center in Boston.The presentation will highlight results from the ongoing Phase I trials primary objectives of defining safety, dose-limiting toxicities, and a recommended phase 2 dose (RP2D).

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