A Phase 2, Multicenter, Randomized, Open-label Study Comparing Fostrox + Lenvatinib vs. Lenvatinib in Patients With Locally Advanced or Unresectable Advanced Hepatocellular Carcinoma (HCC) Who Have Received First-line Combination Immunotherapy
Latest Information Update: 25 May 2026
At a glance
- Drugs Fostroxacitabine bralpamide (Primary) ; Lenvatinib (Primary)
- Indications Liver cancer
- Focus Proof of concept; Registrational; Therapeutic Use
- Acronyms FLEX-HCC
- Sponsors Medivir AB
Most Recent Events
- 22 May 2026 Status changed from not yet recruiting to recruiting.
- 25 Mar 2026 Status changed from planning to not yet recruiting.
- 16 Dec 2025 According to a Medivir AB media release, today announced the approval of the US Investigational New Drug application (IND) for evaluating fostrox + Lenvima vs Lenvima alone in a phase 2b study in 2nd line advanced HCC.