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Efficacy and Safety of Cagrilintide 2.4 mg s.c. in Combination With Semaglutide 2.4 mg s.c. (CagriSema s.c. 2.4 mg/2.4 mg) Once-weekly Compared to Tirzepatide 15 mg s.c. Once-weekly in Participants With Obesity

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Trial Profile

Efficacy and Safety of Cagrilintide 2.4 mg s.c. in Combination With Semaglutide 2.4 mg s.c. (CagriSema s.c. 2.4 mg/2.4 mg) Once-weekly Compared to Tirzepatide 15 mg s.c. Once-weekly in Participants With Obesity

Status: Active, no longer recruiting
Phase of Trial: Phase III

Latest Information Update: 14 Mar 2025

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At a glance

  • Drugs Cagrilintide/semaglutide (Primary) ; Tirzepatide
  • Indications Obesity
  • Focus Registrational; Therapeutic Use
  • Acronyms REDEFINE 4
  • Sponsors Novo Nordisk

Most Recent Events

  • 11 Mar 2025 Planned End Date changed from 21 Oct 2025 to 13 Jan 2026.
  • 20 Aug 2024 Status changed from recruiting to active, no longer recruiting.
  • 05 Dec 2023 Planned End Date changed from 8 Oct 2025 to 21 Oct 2025.

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