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DAREON-7: A Phase I, Open-label, Dose Escalation and Expansion Trial to Investigate Safety and Tolerability of BI 764532 Intravenous Infusions in Combination With Standard of Care (Platinum and Etoposide) in First-line Treatment of Patients With Neuroendocrine Carcinomas (NEC)

Trial Profile

DAREON-7: A Phase I, Open-label, Dose Escalation and Expansion Trial to Investigate Safety and Tolerability of BI 764532 Intravenous Infusions in Combination With Standard of Care (Platinum and Etoposide) in First-line Treatment of Patients With Neuroendocrine Carcinomas (NEC)

Status: Active, no longer recruiting
Phase of Trial: Phase I

Latest Information Update: 07 Sep 2026

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At a glance

  • Drugs Carboplatin (Primary) ; Cisplatin (Primary) ; Etoposide (Primary) ; Obrixtamig (Primary)
  • Indications Neuroendocrine carcinoma
  • Focus Adverse reactions
  • Acronyms DAREON™-7
  • Sponsors Boehringer Ingelheim; Boehringer Ingelheim GmbH International

Most Recent Events

  • 29 Jun 2026 This trial has been completed in Germany.
  • 23 Jun 2026 Planned End Date changed from 25 Apr 2027 to 31 Dec 2027.
  • 23 Jun 2026 Planned primary completion date changed from 9 Feb 2027 to 9 Oct 2027.

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