DAREON-7: A Phase I, Open-label, Dose Escalation and Expansion Trial to Investigate Safety and Tolerability of BI 764532 Intravenous Infusions in Combination With Standard of Care (Platinum and Etoposide) in First-line Treatment of Patients With Neuroendocrine Carcinomas (NEC)

Status: Recruiting

Phase of Trial: Phase I

Latest Information Update: 20 Feb 2025

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At a glance

Drugs Carboplatin (Primary) ; Cisplatin (Primary) ; Etoposide (Primary) ; Obrixtamig (Primary)
Indications Neuroendocrine carcinoma
Focus Adverse reactions
Acronyms DAREON™-7
Sponsors Boehringer Ingelheim

Most Recent Events

30 Oct 2024 Planned End Date changed from 1 Dec 2025 to 10 Aug 2026.
30 Oct 2024 Planned primary completion date changed from 5 Nov 2025 to 6 Jul 2026.
10 Apr 2024 Trial design, presented at the 115th Annual Meeting of the American Association for Cancer Research

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