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A Phase 1a/1b Randomized, Double-Blind, Placebo-Controlled, 3-Part Study to Investigate the Safety, Pharmacokinetics, and Pharmacodynamics of Single and Multiple Subcutaneous Doses of TRB-061 in Healthy Participants and in Patients With Moderate-to-Severe Atopic Dermatitis

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Trial Profile

A Phase 1a/1b Randomized, Double-Blind, Placebo-Controlled, 3-Part Study to Investigate the Safety, Pharmacokinetics, and Pharmacodynamics of Single and Multiple Subcutaneous Doses of TRB-061 in Healthy Participants and in Patients With Moderate-to-Severe Atopic Dermatitis

Status: Recruiting
Phase of Trial: Phase I

Latest Information Update: 28 Aug 2025

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At a glance

  • Drugs TRB 061 (Primary)
  • Indications Atopic dermatitis
  • Focus Adverse reactions; First in man; Proof of concept
  • Sponsors TRexBio

Most Recent Events

  • 03 Jun 2025 According to a TRexBio media release, status changed from planning to recruiting.
  • 03 Jun 2025 According to a TRexBio media release, the company has initiated dosing of healthy volunteers in this trial. Safety, pharmacokinetic, and pharmacodynamic data from this study are anticipated in1H 2026.
  • 13 Nov 2024 According to a TRexBio media release, the company announced the close of an oversubscribed $84 million Series B financing round. The funding from this Series B financing enables company to enter the clinic early next year with TRB-061

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