Trial Profile

PRIMROSE: A Modular Phase I/IIa, Multi-centre, Dose Escalation, and Expansion Study of AZD3470, a MTA Cooperative PRMT5 Inhibitor, as Monotherapy and in Combination With Anticancer Agents in Patients With Advanced/Metastatic Solid Tumors That Are MTAP Deficient

Status: Recruiting

Phase of Trial: Phase I/II

Latest Information Update: 13 May 2025

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At a glance

07 May 2025 Planned End Date changed from 27 Feb 2026 to 27 May 2026.
07 May 2025 Planned primary completion date changed from 27 Feb 2026 to 27 May 2026.
19 Dec 2024 Planned number of patients changed from 210 to 234.

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