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A PHASE 1, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED STUDY TO EVALUATE THE SAFETY, TOLERABILITY, PHARMACOKINETICS, AND PHARMACODYNAMICS OF SINGLE ESCALATING DOSES OF PF-07868489 IN HEALTHY ADULT PARTICIPANTS AND REPEAT DOSES IN PARTICIPANTS WITH PULMONARY ARTERIAL HYPERTENSION

Trial Profile

A PHASE 1, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED STUDY TO EVALUATE THE SAFETY, TOLERABILITY, PHARMACOKINETICS, AND PHARMACODYNAMICS OF SINGLE ESCALATING DOSES OF PF-07868489 IN HEALTHY ADULT PARTICIPANTS AND REPEAT DOSES IN PARTICIPANTS WITH PULMONARY ARTERIAL HYPERTENSION

Status: Recruiting
Phase of Trial: Phase I/II

Latest Information Update: 23 Apr 2025

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At a glance

  • Drugs PF-07868489 (Primary)
  • Indications Pulmonary arterial hypertension
  • Focus Adverse reactions
  • Sponsors Pfizer

Most Recent Events

  • 20 Apr 2025 Planned End Date changed from 11 Feb 2027 to 13 Feb 2027.
  • 20 Apr 2025 Planned primary completion date changed from 11 Feb 2027 to 13 Feb 2027.
  • 29 Oct 2024 Planned End Date changed from 12 Jan 2027 to 11 Feb 2027.

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