Trial Profile

A Phase 1 Clinical Study to Investigate the Safety and Pharmacokinetics of MK-5684 in China Participants With Metastatic Castration-Resistant Prostate Cancer

Status: Active, no longer recruiting

Phase of Trial: Phase I

Latest Information Update: 24 Feb 2026

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At a glance

Drugs Dexamethasone (Primary) ; Fludrocortisone (Primary) ; Opevesostat (Primary) ; Hydrocortisone
Indications Adenocarcinoma; Prostate cancer
Focus Adverse reactions; Pharmacokinetics
Acronyms MK-5684-001
Sponsors Merck Sharp & Dohme

Most Recent Events

17 Feb 2026 Planned End Date changed from 14 Mar 2027 to 10 Mar 2026.
17 Feb 2026 Planned primary completion date changed from 14 Nov 2025 to 10 Mar 2026.
05 Feb 2026 Actual primary completion date changed from 26 Nov 2025 to 30 Nov 2025.

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