Randomized, Open-label, Multicenter, Phase 3 Trial of Repotrectinib Versus Crizotinib in Participants With Locally Advanced or Metastatic Tyrosine Kinase Inhibitor (TKI)-naïve ROS1-positive Non-Small Cell Lung Cancer (NSCLC) (TRIDENT-3)
Latest Information Update: 20 May 2025
At a glance
- Drugs Repotrectinib (Primary) ; Crizotinib
- Indications Non-small cell lung cancer
- Focus Registrational; Therapeutic Use
- Acronyms TRIDENT-3
- Sponsors Bristol-Myers Squibb
Most Recent Events
- 06 May 2025 Planned number of patients changed from 230 to 190.
- 06 May 2025 Planned End Date changed from 27 Jan 2031 to 3 Jun 2027.
- 06 May 2025 Planned primary completion date changed from 26 Feb 2029 to 3 Jun 2027.