Trial Profile

3-Pillars Study: a phase II open label study of the cyclin-dependent kinase 4/6 inhibitor palbociclib in combination with letrozole, trastuzumab plus tucatinib as neoadjuvant treatment for ER-positive, PgR-positive and HER2-positive early breast cancer in post-menopausal women

Status: Recruiting

Phase of Trial: Phase II

Latest Information Update: 06 Feb 2024

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At a glance

Drugs Estrogen (Primary) ; Letrozole (Primary) ; Palbociclib (Primary) ; Trastuzumab (Primary) ; Tucatinib (Primary)
Indications Early breast cancer; HER2 positive breast cancer
Focus Therapeutic Use
Acronyms 3-Pillars Study

24 Nov 2023 Recruitment completion is expected on 01 Jun 2025 according to ISRCTN Clinical Trials Registry Record.
24 Nov 2023 New trial record

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