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Phase I/IB Trial of Radiotherapy in Combination With TTI-101 in Borderline Resectable and Locally Advanced Pancreatic Ductal Adenocarcinoma

Trial Profile

Phase I/IB Trial of Radiotherapy in Combination With TTI-101 in Borderline Resectable and Locally Advanced Pancreatic Ductal Adenocarcinoma

Status: Recruiting
Phase of Trial: Phase I

Latest Information Update: 13 Sep 2026

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At a glance

  • Drugs TTI 101 (Primary)
  • Indications Adenocarcinoma; Pancreatic ductal carcinoma
  • Focus Adverse reactions

Most Recent Events

  • 21 Aug 2026 Planned number of patients changed from 18 to 24.
  • 27 May 2026 Status changed from active, no longer recruiting to recruiting.
  • 17 Mar 2026 Given protocol has been amended as above- 1) status changed to active, no longer recruiting. 2) Planned primary completion and planned end date changed to 30 Jun 2029. 3) Open label design has been amended. 4) Primary endpoints has been amended. 5) Number of treatment arms has been changed from 2 to 4. 6) Actual patient number is 5.

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