Trial Profile

An Investigational Study of CX-801 as Monotherapy and in Combination With PD1 Inhibition in Participants With Solid Tumors

Status: Recruiting

Phase of Trial: Phase I

Latest Information Update: 03 Dec 2025

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At a glance

Drugs CX 801 (Primary) ; Pembrolizumab (Primary)
Indications Head and neck cancer; Malignant melanoma; Renal cancer; Solid tumours; Squamous cell cancer
Focus Adverse reactions; First in man
Sponsors CytomX Therapeutics

06 Nov 2025 According to a CytomX Therapeutics media release, study currently enrolling the 2nd dose level.
04 Nov 2025 According to a CytomX Therapeutics media release, data from the trial will be presented at the Society for Immunotherapy of Cancer (SITC) 40th Anniversary Annual Meeting
07 Aug 2025 According to a CytomX Therapeutics media release,dose escalation of CX-801 in combination with KEYTRUDA was initiated and Initial clinical data for the combination therapy in advanced melanoma is anticipated in 2026.

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