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An Open-label, Single-arm Treatment Study to Investigate the Safety and Tolerability of Switching From Emicizumab to Fitusiran Prophylaxis in Male Participants Aged ≥18 Years of Age With Severe Hemophilia A, With or Without Inhibitors

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Trial Profile

An Open-label, Single-arm Treatment Study to Investigate the Safety and Tolerability of Switching From Emicizumab to Fitusiran Prophylaxis in Male Participants Aged ≥18 Years of Age With Severe Hemophilia A, With or Without Inhibitors

Status: Recruiting
Phase of Trial: Phase I

Latest Information Update: 14 Mar 2024

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At a glance

  • Drugs Fitusiran (Primary) ; Antithrombins; Emicizumab
  • Indications Haemophilia A
  • Focus Adverse reactions
  • Sponsors Sanofi

    • Most Recent Events

    • 06 Mar 2024 Planned End Date changed from 3 Feb 2028 to 19 May 2028.
    • 06 Mar 2024 Planned primary completion date changed from 15 May 2026 to 19 Sep 2026.
    • 06 Mar 2024 Status changed from not yet recruiting to recruiting.

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