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A Phase 2b, Randomised, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy, Safety, and Tolerability of 3 Dose Levels of NMD670 Over 21 Days in Adult Patients With AChR/MuSK-Ab+ Myasthenia Gravis

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Trial Profile

A Phase 2b, Randomised, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy, Safety, and Tolerability of 3 Dose Levels of NMD670 Over 21 Days in Adult Patients With AChR/MuSK-Ab+ Myasthenia Gravis

Status: Recruiting
Phase of Trial: Phase II

Latest Information Update: 25 Feb 2025

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At a glance

  • Drugs Bromophenoxyazole propanoic acid (Primary)
  • Indications Myasthenia gravis
  • Focus Proof of concept; Therapeutic Use
  • Acronyms SYNAPSE-MG
  • Sponsors NMD Pharma
  • Most Recent Events

    • 06 Jan 2025 According to a NMD Pharma media release, the company has three ongoing global clinical trials investigating NMD670 including a Phase 2 study in adults living with spinal muscular atrophy (SMA) type 3, a Phase 2b study in gMG patients, and this Phase 2 CMT study, with data readout(s) occurring from 2H/2025 through 1H/2026.
    • 01 Oct 2024 According to NMD Pharma media release, company will present design, progress and improvement in QMG score and skeletal muscle function data from this phase 2b trial in an oral presentation during the Myasthenia Gravis Foundation of America (MGFA) Scientific Sessions, which will be held in Chatham Ballroom A in the Savannah Convention Center on Tuesday, 15 October from 8:00 am-12:00 pm.
    • 11 Jun 2024 Status changed from not yet recruiting to recruiting, according to NMD Pharma media release.

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