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A Phase 1, Randomized, Double-blind, Placebo-controlled, First-in-human, Single and Multiple Ascending Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Prodrug BMS-986465 and Its Active Derivative, BMS-986464, in Healthy Participants Including Healthy Participants of Japanese Ethnicity and an Open-label Assessment of Food, Formulation, and pH Effects on the Relative Bioavailability of BMS-986465 and BMS-986464

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Trial Profile

A Phase 1, Randomized, Double-blind, Placebo-controlled, First-in-human, Single and Multiple Ascending Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Prodrug BMS-986465 and Its Active Derivative, BMS-986464, in Healthy Participants Including Healthy Participants of Japanese Ethnicity and an Open-label Assessment of Food, Formulation, and pH Effects on the Relative Bioavailability of BMS-986465 and BMS-986464

Status: Discontinued
Phase of Trial: Phase I

Latest Information Update: 10 Feb 2025

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At a glance

  • Drugs BMS 986465 (Primary) ; Famotidine; Peginterferon alfa-2a
  • Indications Unspecified
  • Focus Adverse reactions; First in man
  • Sponsors Bristol-Myers Squibb

Most Recent Events

  • 06 Feb 2025 Status changed from active, no longer recruiting to discontinued.
  • 28 Nov 2024 Status changed from recruiting to active, no longer recruiting.
  • 22 Apr 2024 Status changed from not yet recruiting to recruiting.

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