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A Phase 2, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Assess the Efficacy, Safety, and Tolerability of NBI-1070770 in Adults With Major Depressive Disorder

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Trial Profile

A Phase 2, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Assess the Efficacy, Safety, and Tolerability of NBI-1070770 in Adults With Major Depressive Disorder

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 03 Dec 2025

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At a glance

  • Drugs NBI-1070770 (Primary)
  • Indications Major depressive disorder
  • Focus Therapeutic Use
  • Sponsors Neurocrine Biosciences

Most Recent Events

  • 10 Nov 2025 Primary endpoint has not been met. (Change in Total Montgomery-sberg Depression Rating Scale (MADRS) Score from Baseline to Day 5)
  • 29 Oct 2025 Status changed from active, no longer recruiting to completed.
  • 22 Sep 2025 Status changed from recruiting to active, no longer recruiting.

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