Trial Profile

A Platform Study of RAS(ON) Inhibitors in Patients With RAS-Mutated Non-Small Cell Lung Cancer (NSCLC)

Status: Recruiting

Phase of Trial: Phase I/II

Latest Information Update: 11 Jul 2025

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At a glance

Drugs Carboplatin (Primary) ; Cisplatin (Primary) ; Daraxonrasib (Primary) ; Elironrasib (Primary) ; Pembrolizumab (Primary) ; Pemetrexed (Primary) ; Zoldonrasib (Primary)
Indications Non-small cell lung cancer; Solid tumours
Focus Adverse reactions
Acronyms RMC-LUNG-101B; RMC-LUNG101
Sponsors REVOLUTION Medicines

Most Recent Events

02 Jul 2025 Study protocol amended with addition of Subprotocol D: RMC-9805. Arms increased from 3 to 4.
02 Jul 2025 Planned number of patients changed from 484 to 616.
07 Jan 2025 The protocol has been amended.

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