Trial Profile

A Phase I, Open-label, Fixed-sequence, Drug Interaction Study to Investigate the Effect of Multiple Oral Doses of Pirtobrutinib (LOXO-305) on the Pharmacokinetics of Repaglinide (CYP2C8 Substrate) in Healthy Subjects

Status: Completed

Phase of Trial: Phase I

Latest Information Update: 19 Mar 2025

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At a glance

Drugs Pirtobrutinib (Primary) ; Repaglinide
Indications Chronic lymphocytic leukaemia; Haematological malignancies; Mantle-cell lymphoma; Marginal zone B-cell lymphoma; Non-Hodgkin's lymphoma; Waldenstrom's macroglobulinaemia
Focus Pharmacokinetics
Sponsors Eli Lilly and Company

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