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A Randomized, Double-Blind, Placebo-Controlled, Phase 3 Study to Evaluate the Safety and Efficacy of Fazirsiran in the Treatment of Alpha-1 Antitrypsin Deficiency-Associated Liver Disease With METAVIR Stage F1 Fibrosis

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Trial Profile

A Randomized, Double-Blind, Placebo-Controlled, Phase 3 Study to Evaluate the Safety and Efficacy of Fazirsiran in the Treatment of Alpha-1 Antitrypsin Deficiency-Associated Liver Disease With METAVIR Stage F1 Fibrosis

Status: Recruiting
Phase of Trial: Phase III

Latest Information Update: 15 Jun 2025

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At a glance

  • Drugs Fazirsiran (Primary)
  • Indications Alpha 1-antitrypsin deficiency
  • Focus Adverse reactions; Registrational; Therapeutic Use
  • Acronyms Fibrosis
  • Sponsors Takeda

Most Recent Events

  • 04 Mar 2024 Status changed from not yet recruiting to recruiting.
  • 24 Jan 2024 Planned initiation date changed from 18 Jan 2024 to 15 Feb 2024.
  • 14 Dec 2023 New trial record

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