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A Phase 1b Study to Assess the Safety, Tolerability, and Efficacy of TAS-120 (Futibatinib) in Combination with MK-3475 (Pembrolizumab) in Patients with Solid Tumors (MK3475 - 990)

Trial Profile

A Phase 1b Study to Assess the Safety, Tolerability, and Efficacy of TAS-120 (Futibatinib) in Combination with MK-3475 (Pembrolizumab) in Patients with Solid Tumors (MK3475 - 990)

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 14 Oct 2024

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At a glance

  • Drugs Futibatinib (Primary) ; Pembrolizumab (Primary) ; Cisplatin; Fluorouracil
  • Indications Non-small cell lung cancer; Oesophageal cancer; Solid tumours
  • Focus Adverse reactions; Therapeutic Use
  • Sponsors Taiho Pharmaceutical
  • Most Recent Events

    • 04 Jun 2024 Results(As of October 31, 2023, 36 pts ) presented at the 60th Annual Meeting of the American Society of Clinical Oncology
    • 14 Dec 2023 New trial record
    • 24 Oct 2023 Updated results of antitumor activity and tolerability results in combination with chemotherapy, presented at the 48th European Society for Medical Oncology Congress

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