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A Phase 1b/II, Open-label Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Efficacy of D-1553 Combined With IN10018 in Subjects With Locally Advanced or Metastatic Solid Tumors With KRAS G12C Mutation

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Trial Profile

A Phase 1b/II, Open-label Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Efficacy of D-1553 Combined With IN10018 in Subjects With Locally Advanced or Metastatic Solid Tumors With KRAS G12C Mutation

Status: Recruiting
Phase of Trial: Phase I/II

Latest Information Update: 23 Jan 2026

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At a glance

  • Drugs Garsorasib (Primary) ; Ifebemtinib (Primary)
  • Indications Colorectal cancer; Non-small cell lung cancer; Solid tumours
  • Focus Adverse reactions; Therapeutic Use
  • Sponsors InxMed

Most Recent Events

  • 16 Jan 2026 Planned End Date changed from 31 Dec 2026 to 31 Dec 2027.
  • 16 Jan 2026 Planned primary completion date changed from 31 Dec 2025 to 31 Dec 2027.
  • 01 Jun 2025 According to the InxMed Media Release, the clinical data from this study presented at the 2025 ASCO Annual Meeting.

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