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A Phase 1b/II, Open-label Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Efficacy of D-1553 Combined With IN10018 in Subjects With Locally Advanced or Metastatic Solid Tumors With KRAS G12C Mutation

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Trial Profile

A Phase 1b/II, Open-label Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Efficacy of D-1553 Combined With IN10018 in Subjects With Locally Advanced or Metastatic Solid Tumors With KRAS G12C Mutation

Status: Active, no longer recruiting
Phase of Trial: Phase I/II

Latest Information Update: 06 Sep 2026

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At a glance

  • Drugs Garsorasib (Primary) ; Ifebemtinib (Primary)
  • Indications Colorectal cancer; Non-small cell lung cancer; Solid tumours
  • Focus Adverse reactions; Therapeutic Use
  • Sponsors InxMed

Most Recent Events

  • 28 Aug 2026 According to an InxMed media release, results from this trial have been published online in The Lancet Oncology.
  • 28 Aug 2026 Results presented in the InxMed media release.
  • 25 Mar 2026 Status changed from recruiting to active, no longer recruiting.

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