A Randomized, Double-blind, Placebo-controlled, Multicenter Study to Evaluate the Efficacy and Safety of Zilebesiran Used as Add-on Therapy in Adult Patients With High Cardiovascular Risk and Hypertension Not Adequately Controlled by Standard of Care Antihypertensive Medications
Latest Information Update: 26 May 2025
At a glance
- Drugs Zilebesiran (Primary)
- Indications Hypertension
- Focus Therapeutic Use
- Acronyms KARDIA-3
- Sponsors Alnylam Pharmaceuticals
Most Recent Events
- 20 Jan 2025 Status changed from recruiting to active, no longer recruiting.
- 12 Jan 2025 According to Alnylam Pharmaceuticals media release, company plans to report results from the KARDIA-3 Phase 2 study in the second half of 2025.
- 03 Jun 2024 KARDIA-3 will initiate enrollment in early 2024, according to trial design in presented 33rd European meeting on hypertension and cardiovascular protection.