A phase III randomized study comparing talquetamab in combination with pomalidomide (Tal-P), talquetamab in combination with teclistamab (Tal-Tec), and investigator's choice of either elotuzumab, pomalidomide, and dexamethasone (EPd) or pomalidomide, bortezomib, and dexamethasone (PVd) in participants with relapsed or refractory myeloma who have received 1 to 4 prior lines of therapy including an Anti-CD38 antibody and lenalidomide
Latest Information Update: 20 Aug 2025
At a glance
- Drugs Bortezomib (Primary) ; Dexamethasone (Primary) ; Dexamethasone (Primary) ; Elotuzumab (Primary) ; Pomalidomide (Primary) ; Talquetamab (Primary) ; Teclistamab (Primary)
- Indications Multiple myeloma
- Focus Registrational; Therapeutic Use
- Acronyms MonumenTAL-6
- Sponsors Janssen Research & Development
Most Recent Events
- 10 Dec 2024 Trial design presented at the 66th American Society of Hematology Annual Meeting and Exposition.
- 23 Apr 2024 Planned primary completion date changed from 14 Jun 2027 to 23 Apr 2026.
- 30 Jan 2024 Status changed from not yet recruiting to recruiting.