Trial Profile

A Phase 1b/2a Open-label Single Ascending Doses (SAD) and Multiple Ascending Doses (MAD) Research Study to Evaluate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics in Participants With AATD Pi*ZZ on WVE-006 (RestorAATion-2)

Status: Recruiting

Phase of Trial: Phase I/II

Latest Information Update: 23 Oct 2026

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At a glance

19 Oct 2026 Planned number of patients changed from 24 to 48.
19 Oct 2026 Planned End Date changed from 1 Sep 2026 to 1 Sep 2027.
19 Oct 2026 Planned primary completion date changed from 1 Sep 2026 to 1 Sep 2027.

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