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A Multicenter, Open-Label, Single-Arm, Phase II Trial Exploring the Maintenance of Trastuzumab and Pertuzumab Following Trastuzumab Deruxtecan as Induction Treatment for HER2+ Unresectable Locally Recurrent or Metastatic Breast Cancer

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A Multicenter, Open-Label, Single-Arm, Phase II Trial Exploring the Maintenance of Trastuzumab and Pertuzumab Following Trastuzumab Deruxtecan as Induction Treatment for HER2+ Unresectable Locally Recurrent or Metastatic Breast Cancer

Status: Recruiting
Phase of Trial: Phase II

Latest Information Update: 28 Jan 2025

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At a glance

  • Drugs Pertuzumab/trastuzumab (Primary) ; Trastuzumab-deruxtecan (Primary)
  • Indications Advanced breast cancer; HER2 positive breast cancer
  • Focus Therapeutic Use
  • Acronyms DEMETHER

    • Most Recent Events

    • 13 Dec 2024 Trial design presented at the 47th Annual San Antonio Breast Cancer Symposium
    • 05 Dec 2024 According to MEDSIR media release, this trial is currently being conducted at 23 active centers across the United States, Spain, Italy and Germany.
    • 05 Dec 2024 According to MEDSIR media release, the company will present the data from this study at San Antonio Breast Cancer Symposium 2024.

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