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A Randomized, Open-label, Phase 3 Study of MK-2870 in Combination With Pembrolizumab Compared to Pembrolizumab Monotherapy in the First-line Treatment of Participants With Metastatic Non-small Cell Lung Cancer With PD-L1 TPS Greater Than or Equal to 50% (TroFuse-007)

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A Randomized, Open-label, Phase 3 Study of MK-2870 in Combination With Pembrolizumab Compared to Pembrolizumab Monotherapy in the First-line Treatment of Participants With Metastatic Non-small Cell Lung Cancer With PD-L1 TPS Greater Than or Equal to 50% (TroFuse-007)

Status: Recruiting
Phase of Trial: Phase III

Latest Information Update: 02 Mar 2025

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At a glance

  • Drugs Sacituzumab Tirumotecan (Primary) ; Dexamethasone; Diphenhydramine; Paracetamol; Pembrolizumab
  • Indications Carcinoma; Non-small cell lung cancer; Squamous cell cancer
  • Focus Registrational; Therapeutic Use
  • Acronyms TroFuse-007
  • Sponsors Merck Sharp & Dohme

    • Most Recent Events

    • 10 Apr 2024 Trial design presented at the 115th Annual Meeting of the American Association for Cancer Research.
    • 05 Jan 2024 According to Merck media release, the trial have been initiated and patients are now enrolling.
    • 05 Jan 2024 According to Merck media release Status changed from not yet recruiting to recruiting.

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