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An Open-label, Multicenter Study of ZL-1310 to Evaluate the Safety, Efficacy, and Pharmacokinetics in Participants With Small Cell Lung Cancer

Trial Profile

An Open-label, Multicenter Study of ZL-1310 to Evaluate the Safety, Efficacy, and Pharmacokinetics in Participants With Small Cell Lung Cancer

Status: Recruiting
Phase of Trial: Phase I

Latest Information Update: 26 Jun 2025

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At a glance

  • Drugs Atezolizumab (Primary) ; Carboplatin (Primary) ; ZL 1310 (Primary)
  • Indications Small cell lung cancer
  • Focus Adverse reactions
  • Sponsors ZAI Lab

Most Recent Events

  • 02 Jun 2025 Results presented in the Zai Lab media release.
  • 19 May 2025 According to a Zai Lab media release, company will hold an investor conference call and webcast to highlight updated ZL-1310 data at ASCO and outline the next steps in clinical development.
  • 19 May 2025 According to a Zai Lab media release, company announced the U.S. Food and Drug Administration (FDA) has granted Fast Track designation to ZL-1310, the Companys potential first-in-class Delta-like ligand (DLL3) antibody-drug conjugate (ADC), for the treatment of extensive-stage small cell lung cancer (ES-SCLC). ZL-1310, which is being evaluated in an ongoing global Phase 1a/1b clinical trial.

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