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Phase II Study of Enasidenib in IDH2-mutated Malignant Sinonasal and Skull Base Tumors

Trial Profile

Phase II Study of Enasidenib in IDH2-mutated Malignant Sinonasal and Skull Base Tumors

Status: Recruiting
Phase of Trial: Phase II

Latest Information Update: 15 Mar 2025

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At a glance

  • Drugs Enasidenib (Primary)
  • Indications Adenocarcinoma; Carcinoma; Chondrosarcoma; Multiple hamartoma syndrome; Neuroblastoma; Neuroendocrine carcinoma; Sinonasal-undifferentiated-carcinoma
  • Focus Therapeutic Use

Most Recent Events

  • 17 Jan 2025 Planned number of patients changed from 25 to 40.
  • 10 Jul 2024 According to an abstract published at 60th Annual Meeting of the American Society of Clinical Oncology ,the trial design was discussed along with Planned number of patients changed from 30 to 25.
  • 05 Mar 2024 Planned initiation date (estimated date for recruitment of the first subject) changed from 6 Mar 2024 to 11 Mar 2024.

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