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A Phase 1 Study of JNJ-87890387, an Ectonucleotide Pyrophosphatase/Phosphodiesterase Family Member 3 (ENPP3) x CD3 Bispecific Antibody, for Advanced Solid Tumors

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Trial Profile

A Phase 1 Study of JNJ-87890387, an Ectonucleotide Pyrophosphatase/Phosphodiesterase Family Member 3 (ENPP3) x CD3 Bispecific Antibody, for Advanced Solid Tumors

Status: Recruiting
Phase of Trial: Phase I

Latest Information Update: 05 Apr 2025

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At a glance

  • Drugs JNJ 87890387 (Primary)
  • Indications Adenocarcinoma; Carcinoma; Colorectal cancer; Lung cancer; Ovarian cancer; Renal cell carcinoma; Solid tumours; Uterine cancer
  • Focus Adverse reactions
  • Sponsors Janssen Research & Development

Most Recent Events

  • 03 Feb 2025 Planned End Date changed from 16 Mar 2027 to 21 Dec 2027.
  • 24 Oct 2024 Planned number of patients changed from 140 to 158.
  • 17 Jul 2024 Planned End Date changed from 11 Sep 2026 to 16 Mar 2027.

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