A Phase 3, Randomized, Double-blind, Placebo-controlled, Multicenter Study to Evaluate the Efficacy and Safety of Amyloid Depleter ALXN2220 in Adult Participants With Transthyretin Amyloid Cardiomyopathy (ATTR-CM)
Latest Information Update: 20 Aug 2026
At a glance
- Drugs Cliramitug (Primary)
- Indications Cardiomyopathies
- Focus Registrational; Therapeutic Use
- Acronyms DepleTTR-CM
- Sponsors Alexion AstraZeneca Rare Disease
Most Recent Events
- 10 Aug 2026 Planned End Date changed from 5 Oct 2027 to 5 Apr 2028.
- 10 Aug 2026 Planned primary completion date changed from 7 Jun 2027 to 6 Dec 2027.
- 18 Jun 2025 Planned End Date changed from 31 Oct 2028 to 5 Oct 2027.