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A Phase 1/2, Randomized, Double-blind, Placebo-controlled Single- and Multiple-dose Escalation Study Evaluating the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of VX-670 in Adult Subjects With Myotonic Dystrophy Type 1

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Trial Profile

A Phase 1/2, Randomized, Double-blind, Placebo-controlled Single- and Multiple-dose Escalation Study Evaluating the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of VX-670 in Adult Subjects With Myotonic Dystrophy Type 1

Status: Recruiting
Phase of Trial: Phase I/II

Latest Information Update: 16 Jan 2025

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At a glance

  • Drugs VX 670 (Primary)
  • Indications Myotonic dystrophy
  • Focus Adverse reactions
  • Acronyms Galileo
  • Sponsors Vertex Pharmaceuticals
  • Most Recent Events

    • 12 Jan 2025 According to Vertex Pharmaceuticals media release, the company initiated the MAD portion of the Phase 1/2 study, which will assess both safety and efficacy.
    • 01 Aug 2024 According to Vertex Pharmaceuticals media release, the company is expecting to complete the single ascending dose (SAD) portion of the study by the end of 2024.
    • 07 May 2024 According to an Entrada Therapeutics media release, In March 2024, company a achieved a milestone under its global collaboration with Vertex related to the clinical advancement of Vertex's Phase 1/2 clinical trial of VX-670, which triggered a $75 million payment. The Company expects to receive this payment in the second quarter of 2024.

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