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An Open-label, Multicenter, Phase 2 Dose Optimization and Expansion Study to Evaluate the Safety and Efficacy of BB-1701, an Anti-human Epidermal Growth Factor Receptor 2 (Anti-HER2) Antibody-drug Conjugate (ADC), in Previously Treated Subjects With HER2-positive or HER2-low Unresectable or Metastatic Breast Cancer

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Trial Profile

An Open-label, Multicenter, Phase 2 Dose Optimization and Expansion Study to Evaluate the Safety and Efficacy of BB-1701, an Anti-human Epidermal Growth Factor Receptor 2 (Anti-HER2) Antibody-drug Conjugate (ADC), in Previously Treated Subjects With HER2-positive or HER2-low Unresectable or Metastatic Breast Cancer

Status: Active, no longer recruiting
Phase of Trial: Phase II

Latest Information Update: 25 Mar 2026

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At a glance

  • Drugs BB 1701 (Primary)
  • Indications Advanced breast cancer; HER2 positive breast cancer
  • Focus Adverse reactions; Therapeutic Use
  • Sponsors Eisai Inc

Most Recent Events

  • 20 Mar 2026 Planned End Date changed from 31 Mar 2026 to 31 Mar 2027.
  • 20 Mar 2026 Planned primary completion date changed from 31 Mar 2026 to 31 Mar 2027.
  • 06 Apr 2025 Status changed from recruiting to active, no longer recruiting.

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