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An Open-Label, Dose Escalation Phase 1a Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of MK-1045 (CN201) in Patients With Relapsed or Refractory B-Cell Non-Hodgkin Lymphoma

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Trial Profile

An Open-Label, Dose Escalation Phase 1a Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of MK-1045 (CN201) in Patients With Relapsed or Refractory B-Cell Non-Hodgkin Lymphoma

Status: Recruiting
Phase of Trial: Phase I

Latest Information Update: 07 Apr 2026

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At a glance

  • Drugs CN 201 (Primary)
  • Indications B-cell lymphoma; Chronic lymphocytic leukaemia; Diffuse large B cell lymphoma; Follicular lymphoma; Mantle-cell lymphoma; Marginal zone B-cell lymphoma; Non-Hodgkin's lymphoma; Waldenstrom's macroglobulinaemia
  • Focus Adverse reactions; First in man
  • Sponsors Curon Biopharmaceutical

Most Recent Events

  • 19 Mar 2026 Planned End Date changed from 30 Mar 2029 to 30 Sep 2028.
  • 22 Oct 2025 Planned End Date changed from 30 Sep 2027 to 30 Mar 2029.
  • 13 May 2025 Planned End Date changed from 1 Dec 2025 to 30 Sep 2027.

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