Trial Profile

A Phase 3, Multicenter, Randomized, Open-Label Trial to Evaluate the Safety and Efficacy of Epcoritamab + Rituximab and Lenalidomide (R2) Compared to Chemoimmunotherapy in Previously Untreated Follicular Lymphoma (EPCORE FL-2)

Status: Recruiting

Phase of Trial: Phase III

Latest Information Update: 06 Nov 2025

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At a glance

Drugs Epcoritamab (Primary) ; Lenalidomide (Primary) ; Rituximab (Primary) ; Bendamustine; Cyclophosphamide; Doxorubicin; Obinutuzumab; Prednisone; Vincristine
Indications Follicular lymphoma
Focus Registrational; Therapeutic Use
Acronyms EPCOR FL-2
Sponsors Genmab

30 Apr 2025 Planned number of patients changed from 1080 to 1095.
03 Dec 2024 Planned End Date changed from 18 May 2037 to 1 Nov 2037.
03 Dec 2024 Planned primary completion date changed from 18 May 2037 to 1 Nov 2037.

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