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A Single Center, Non-Randomized, Phase 1b Study of Orca-T Following Escalated Dose of Total Marrow and Lymphoid Irradiation in Patients With Acute Leukemias and MDS

Trial Profile

A Single Center, Non-Randomized, Phase 1b Study of Orca-T Following Escalated Dose of Total Marrow and Lymphoid Irradiation in Patients With Acute Leukemias and MDS

Status: Recruiting
Phase of Trial: Phase I

Latest Information Update: 13 Dec 2024

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At a glance

  • Drugs Fludarabine (Primary) ; Melphalan (Primary) ; Orca-T (Primary) ; Tacrolimus (Primary) ; Thiotepa (Primary)
  • Indications Acute myeloid leukaemia; Myelodysplastic syndromes; Precursor cell lymphoblastic leukaemia-lymphoma
  • Focus Adverse reactions

Most Recent Events

  • 09 Dec 2024 According to a Orca Bio media release, data from the study were presented at the 66th American Society of Hematology (ASH) Annual Meeting.
  • 09 Dec 2024 Results (Three-Year Survival Data, n=77) presented in the Orca Bio Media Release.
  • 23 Feb 2024 Results from a subgroup analysis of this trial presented in a Orca Bio media release.

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