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A Phase 3, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of Orally Administered Deucrictibant Extended-Release Tablet for Prophylaxis Against Angioedema Attacks in Adolescents and Adults with Hereditary Angioedema

Trial Profile

A Phase 3, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of Orally Administered Deucrictibant Extended-Release Tablet for Prophylaxis Against Angioedema Attacks in Adolescents and Adults with Hereditary Angioedema

Status: Active, no longer recruiting
Phase of Trial: Phase III

Latest Information Update: 14 Apr 2026

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At a glance

  • Drugs Deucrictibant (Primary)
  • Indications Hereditary angioedema
  • Focus Registrational; Therapeutic Use
  • Acronyms CHAPTER-3
  • Sponsors Pharvaris

Most Recent Events

  • 02 Apr 2026 According to a Pharvaris media release, company anticipates announcing topline data from the trial in third quarter of 2026.
  • 02 Apr 2026 Status changed from recruiting to active, no longer recruiting.
  • 10 Feb 2026 According to a Pharvaris media release, data from this trial will be presented at the American Academy of Allergy, Asthma & Immunology (AAAAI) 2026 Annual Meeting, to be held from February 27-March 2, 2026, in Philadelphia, PA.

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