Trial Profile

A Phase 3, Randomized Study, With Initial 24-week, Double-Blind and Placebo-Controlled Treatment Phase, Followed by An 80-week Open-label Extension Treatment Phase to Evaluate the Effect of Eplontersen on the Transthyretin Reduction and Long-Term Safety in Chinese Participants With Transthyretin Amyloid Cardiomyopathy (EPIC-ATTR)

Status: Active, no longer recruiting

Phase of Trial: Phase III

Latest Information Update: 08 Oct 2025

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At a glance

11 Sep 2025 Planned End Date changed from 21 Jan 2027 to 5 Jan 2027.
11 Sep 2025 Planned primary completion date changed from 28 Apr 2026 to 14 May 2026.
04 Apr 2025 Planned End Date changed from 26 Mar 2027 to 21 Jan 2027.

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