A Phase 1 Study of ADI-001 Anti-CD20 CAR-engineered Allogeneic Gamma-Delta (γδ) T Cells in Adults with Autoimmune Disease
Latest Information Update: 25 May 2025
At a glance
- Drugs ADI-001 (Primary) ; Cyclophosphamide; Fludarabine
- Indications Anti-neutrophil cytoplasmic antibody-associated vasculitis; Lupus nephritis; Myositis; Stiff-person syndrome; Systemic lupus erythematosus; Systemic scleroderma
- Focus Adverse reactions
- Sponsors Adicet Bio
Most Recent Events
- 06 May 2025 According to Adicet media release, this trial is now open for enrollment to patients with lupus nephritis (LN) and systemic lupus erythematosus (SLE)
- 06 May 2025 According to Adicet media release, the Company expects to initiate enrollment for patients with systemic sclerosis (SSc), idiopathic inflammatory myopathy (IIM), stiff person syndrome (SPS) and anti-neutrophil cytoplasmic autoantibody associated vasculitis (AAV) in the Phase 1 trial in 3Q/2025.
- 06 May 2025 According to Adicet media release, the company expect to report preliminary Phase 1 data in the second half of 2025, subject to study site initiation and patient enrollment.