Trial Profile

A Phase 2, Randomized, Open-Label, Multicenter Study to Evaluate the Safety and Efficacy of FPI-2265 (225Ac-PSMA-I&T) in Patients With PSMA-Positive Metastatic Castration-Resistant Prostate Cancer (mCRPC)

Status: Recruiting

Phase of Trial: Phase II

Latest Information Update: 15 Oct 2025

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At a glance

09 Oct 2025 The protocol has been amended to change in study phase to phase II/III to phase II.
25 Apr 2025 Planned number of patients changed from 60 to 100.
09 May 2024 According to Fusion Pharmaceuticals media release, the first patient has been dosed in the Phase 2 portion of the AlphaBreak trial evaluating FPI-2265 (225Ac-PSMA I&T) in patients with metastatic castration-resistant prostate cancer (mCRPC).

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