Trial Profile

Safety, Tolerability, and Biodistribution of [89Zr]Zr-DFO-APAC (Phase 0) in Subjects With Peripheral Arterial Occlusive Disease / Critical Limb Ischemia (PAOD/CLI) and Healthy Volunteers - an Open Label PET Study (Acronyms: 89Zr = Zirconium-89, DFO = Desferrioxamine, APAC = AntiPlatelet AntiCoagulant, PET/CT = Positron Emission Tomography/Computed Tomography)

Status: Recruiting

Phase of Trial: Phase 0

Latest Information Update: 04 Feb 2025

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At a glance

Drugs Antiplatelet and anticoagulant therapeutic Aplagon (Primary)
Indications Chronic limb-threatening ischemia; Peripheral arterial occlusive disorders
Focus Adverse reactions; Pharmacokinetics
Acronyms CHASE
Sponsors Aplagon

03 Feb 2025 According to Aplagon media release, company is looking forward to announcing clinical results from this trial in 2025 and 2026.
03 Feb 2025 According to Aplagon media release, APAC is also poised to complete this trial in 2025
30 Jan 2025 Planned End Date changed from 1 Mar 2025 to 1 Jun 2025.

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