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To Evaluate the Safety, Efficacy and Pharmacokinetics of ThisCART19A in Patients With Relapsed and Refractory Acute B-cell Leukemia

Trial Profile

To Evaluate the Safety, Efficacy and Pharmacokinetics of ThisCART19A in Patients With Relapsed and Refractory Acute B-cell Leukemia

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 20 Feb 2026

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At a glance

  • Drugs ThisCART 19 (Primary) ; Cyclophosphamide; Etoposide; Fludarabine
  • Indications Precursor B-cell lymphoblastic leukaemia-lymphoma
  • Focus Adverse reactions

Most Recent Events

  • 17 Feb 2026 Number of treatment arms are decreased from 3 to 2 by the removal of Experimental: ThisCART19A 12x10^6 cells/kg as dose level 3 arm. Doses in the existing 2 arms are also reduced.
  • 17 Feb 2026 Actual Primary Completion Date is 21 May 2025.
  • 17 Feb 2026 Status changed from recruiting to completed.

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