Trial Profile

NHL35 -An Australasian Leukaemia and Lymphoma Group open label phase II study of the effect of of R-CHOP in combination with pembrolizumab in patients with newly diagnosed primary mediastinal B Cell Lymphoma (PMBL)

Status: Recruiting

Phase of Trial: Phase II

Latest Information Update: 12 Feb 2025

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At a glance

Drugs Cyclophosphamide (Primary) ; Doxorubicin (Primary) ; Pembrolizumab (Primary) ; Prednisolone (Primary) ; Rituximab (Primary) ; Vincristine (Primary)
Indications Diffuse large B cell lymphoma
Focus Therapeutic Use
Acronyms ALLG-PACIFIC

19 Jan 2024 Status changed from not yet recruiting to recruiting.
19 Jan 2024 New trial record
12 Dec 2023 Results, assessing the efficacy and safety of this novel, time-limited, radiotherapy sparing regimen, were presented at the 65th American Society of Hematology Annual Meeting and Exposition.

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