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Randomized, Double-Blind, Placebo-Controlled Phase 1 Study to Evaluate Safety, Tolerability, PK/PD of SAD, MAD and Food Effect of Leucettinib-21 in Healthy Male Subjects, and Single Dose in Subjects With Down Syndrome or Alzheimer's Disease

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Trial Profile

Randomized, Double-Blind, Placebo-Controlled Phase 1 Study to Evaluate Safety, Tolerability, PK/PD of SAD, MAD and Food Effect of Leucettinib-21 in Healthy Male Subjects, and Single Dose in Subjects With Down Syndrome or Alzheimer's Disease

Status: Recruiting
Phase of Trial: Phase I

Latest Information Update: 05 Jun 2025

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At a glance

  • Drugs Leucettinib 21 (Primary)
  • Indications Alzheimer's disease; Down syndrome
  • Focus Adverse reactions; First in man; Pharmacokinetics
  • Acronyms LEUCETTA
  • Sponsors Perha Pharmaceuticals

Most Recent Events

  • 31 May 2025 Planned End Date changed from 1 Aug 2024 to 1 Jul 2025.
  • 31 May 2025 Planned primary completion date changed from 1 Aug 2024 to 1 Jul 2025.
  • 19 Feb 2024 Status changed from not yet recruiting to recruiting.

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