Trial Profile

Optimal Precision TherapIes to CustoMISE Care in Childhood and Adolescent Cancer

Status: Recruiting

Phase of Trial: Phase I/II

Latest Information Update: 11 Dec 2025

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At a glance

Drugs Irinotecan (Primary) ; Paxalisib (Primary) ; Temozolomide (Primary) ; Pimasertib
Indications Lymphoma; Solid tumours
Focus Adverse reactions; Therapeutic Use
Acronyms OPTIMISE

Most Recent Events

28 Nov 2025 Planned number of patients changed from 82 to 90.
12 Jul 2024 Status changed from not yet recruiting to recruiting.
22 Jan 2024 New trial record

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