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A Phase 1, Double-Blind, Randomized, Placebo-Controlled, Single-Dose, Dose-Escalation, Drug-Interaction, and Food-Effect Study to Assess the Safety, Tolerability, and Pharmacokinetics of INCB160058 When Administered Orally to Healthy Adult Participants

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Trial Profile

A Phase 1, Double-Blind, Randomized, Placebo-Controlled, Single-Dose, Dose-Escalation, Drug-Interaction, and Food-Effect Study to Assess the Safety, Tolerability, and Pharmacokinetics of INCB160058 When Administered Orally to Healthy Adult Participants

Status: Recruiting
Phase of Trial: Phase I

Latest Information Update: 07 May 2025

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At a glance

  • Drugs Esomeprazole (Primary) ; INCB 160058 (Primary)
  • Indications Myeloproliferative disorders
  • Focus Adverse reactions; Pharmacokinetics
  • Sponsors Incyte Corporation

Most Recent Events

  • 29 Apr 2025 According to Incyte corporation media release, initial proof of concept data expected in 2025.
  • 14 Mar 2025 Planned number of patients changed from 108 to 180.
  • 14 Mar 2025 Planned End Date changed from 29 Sep 2025 to 19 Nov 2025.

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