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A pilot study of indigenously manufactured HCAR19 (2nd generation Anti-CD19-41BB- CD3ζ chimeric antigen receptor T-cell therapy) in adult patients with relapsed/refractory diffuse large B-cell lymphoma.

Trial Profile

A pilot study of indigenously manufactured HCAR19 (2nd generation Anti-CD19-41BB- CD3ζ chimeric antigen receptor T-cell therapy) in adult patients with relapsed/refractory diffuse large B-cell lymphoma.

Status: Active, no longer recruiting
Phase of Trial: Phase I/II

Latest Information Update: 30 Jan 2024

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At a glance

  • Drugs Talicabtagene autoleucel (Primary)
  • Indications B-cell lymphoma; Diffuse large B cell lymphoma; Follicular lymphoma; Precursor B-cell lymphoblastic leukaemia-lymphoma
  • Focus Adverse reactions; Therapeutic Use
  • Most Recent Events

    • 30 Jan 2024 New trial record
    • 12 Dec 2023 Pooled results from Phase I and a planned interim analysis of the Phase II study evaluating Actaly-celpresented at the 65th American Society of Hematology Annual Meeting and Exposition

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